The scientific efforts of the Center investigators are grouped into 5 major themes with a lead scientist who is responsible for monitoring progress, fostering communication, and ensuring integration among workers within their theme. Additional participants within a theme contribute to honing theme directions and expectations. Several participants will engage across multiple themes. With this cross-linked structure, we can facilitate connections and be alert for boundaries or “fault lines” that develop between subgroups within the project. The Center is led by and populated with accomplished scientists possessing varied research expertise. Importantly, the leadership has extensive experience in designing, organizing, and executing multi and single-investigator research efforts for DOE, NSF, and industry as well as experience in managing laboratory and numerical science. Additionally, the leadership team has extensive expertise leveraging efforts at DOE and university user facilities. The key participants are acknowledged as influential and productive scientists in the U.S. and internationally.